Depending on your firmware and if you have 1Gbit networking at your disposal, make sure to check your NIC for a Jumbo Frames setting (right click on your connection, choose properties, then Configure the adapter, look under Advanced) - the Linkstation supports Jumbo Frames up to 9k in size - Mine maxes out at 7k with my realtek onboard NIC, but just by configuring this (assuming your switches, etc can support this) you should see a speed improvement.
I just gained about 4Mb/sec average improved transfer speed. Always welcome when shifting around gigs of data.
My switch everything is plugged into is a ZyXEL GS-108B and supports Jumbo Frames up to 9k, so it would seem the limit here is my onbaord 1Gb NICs.
My router is a DG834 and should only be used for DHCP by the NAS. Although I dont think these home routers directly support the Jumbo Frames, it doesnt seem to be affecting the speed. When I tried plugging the NAS directly into my spare Gbit onboard port, it would transfer files fine at almost the same speed for 1Gbps/7k frames, but the web browser interface and NAS Navigator didnt seem to like it and would either not detect it or did so very slowly. I suspect this relates to the DHCP settings. Possibly CPU overhead too.
So, if your hardware supports it I would suggest it is worth spending 10 mins reconfiguring it and trying Jumbo Frames, you might be surprised by the speed improvement.
My net speed doesnt seem to have been affected by this changeover either